Description

4-(Hydroxymethyl)Piperidine-1-Carbaldehyde is a versatile bifunctional organic building block featuring both a reactive aldehyde group and a hydroxymethyl substituent on a piperidine scaffold. This unique structure makes it a critical intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the piperidine moiety can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Functional monomer for modifying polymer backbones, introducing aldehyde groups for further cross-linking or conjugation.
• Chemical Biology & Proteomics: Useful for synthesizing probes, linkers, or affinity tags due to its reactive aldehyde handle for bioconjugation.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized piperidine derivatives.

Basic Information

Product Name	4-(Hydroxymethyl)Piperidine-1-Carbaldehyde
CAS No.	835633-50-6
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	1-Formyl-4-(hydroxymethyl)piperidine; 4-(Hydroxymethyl)-1-piperidinecarboxaldehyde; 4-Piperidinemethanol, 1-formyl-; 1-Piperidinecarboxaldehyde, 4-(hydroxymethyl)-; N-Formyl-4-piperidinemethanol; 4-(Hydroxymethyl)piperidine-1-carboxaldehyde; Piperidine-1-carbaldehyde, 4-(hydroxymethyl)-
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Piperidine-1-Carbaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay and impurity profiles. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and hydrolysis. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.