Description

4-Amino-3-Nitrophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS research.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products by introducing specific aromatic amine-nitro functional groups.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and molecular probes for studying biological pathways and protein interactions.
• Ligand and Catalyst Development: Acts as a starting material for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Academic & R&D Laboratories: A versatile reagent for methodological development in organic chemistry and exploring new synthetic routes.

Basic Information

Product Name	4-Amino-3-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	833486-94-5
Molecular Formula	C12H17BN2O4
Molecular Weight	264.09 g/mol
Synonyms	4-Amino-3-nitrophenylboronic acid pinacol ester; 2-(4-Amino-3-nitrophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Amino-3-nitrobenzeneboronic acid pinacol ester; Pinacol (4-Amino-3-nitrophenyl)boronate; 4-Amino-3-nitrophenyl-B(pin); B-(4-Amino-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Nitro-4-aminophenylboronic acid pinacol ester; (4-Amino-3-nitrophenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Nitrophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage to prevent hydrolysis of the boronic ester. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.