Description

5-(4-Fluorophenyl)-7-(Pentafluoroethyl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-2-Carbohydrazide is a high-value, fluorinated heterocyclic building block designed for advanced pharmaceutical and agrochemical research. Its complex pyrazolopyrimidine core, functionalized with fluorophenyl and pentafluoroethyl groups, makes it a critical intermediate for synthesizing novel bioactive compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate unique fluorinated motifs into their molecular libraries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Chemical Biology Probe: Serves as a scaffold for creating fluorescent tags or activity-based probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or organic electronic materials with tailored properties.
• Medicinal Chemistry SAR Studies: Enables structure-activity relationship (SAR) exploration around the pyrazolopyrimidine pharmacophore to optimize potency and selectivity.
• Process Chemistry & Scale-Up: Supplied for route scouting and optimization from milligram to kilogram scale under cGMP or non-GMP conditions.

Basic Information

Product Name	5-(4-Fluorophenyl)-7-(Pentafluoroethyl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-2-Carbohydrazide
CAS No.	832739-62-5
Molecular Formula	C₁₅H₁₁F₆N₅O
Molecular Weight	391.27 g/mol
Synonyms	5-(4-Fluorophenyl)-7-(pentafluoroethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carbohydrazide; 5-(4-Fluorophenyl)-7-(pentafluoroethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid hydrazide; 832739-62-5; Pyrazolo[1,5-a]pyrimidine-2-carbohydrazide, 5-(4-fluorophenyl)-7-(pentafluoroethyl)-4,5,6,7-tetrahydro-; 4,5,6,7-Tetrahydro-5-(4-fluorophenyl)-7-(pentafluoroethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)-7-(Pentafluoroethyl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-2-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas when appropriate to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.