Description

2-Benzyloxypyridine-5-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by facilitating the creation of complex heterocyclic structures.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Organic Electronics: Serves as a building block for conjugated polymers and small molecules used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploring new synthetic pathways in laboratory settings.

Basic Information

Product Name	2-Benzyloxypyridine-5-Boronic Acid, Pinacol Ester
CAS No.	832735-54-3
Molecular Formula	C₁₈H₂₂BNO₃
Molecular Weight	311.19 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(benzyloxy)pyridine; 2-(Benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Benzyloxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(Phenylmethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Benzyloxy-5-pyridineboronic acid pinacol ester; 5-Boronic acid, 2-(phenylmethoxy)-, pinacol ester, pyridine-5-boronic acid derivative
EINECS	Contact for details

Quality Control

Our 2-Benzyloxypyridine-5-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced R&D customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.