Description

Elagolix Sodium is the sodium salt form of elagolix, a potent, orally active, non-peptide gonadotropin-releasing hormone (GnRH) receptor antagonist. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacturing of targeted hormonal therapies. It is primarily utilized by pharmaceutical companies and research institutions engaged in advanced therapeutic areas, including women's health and endocrinology.

Application

• Primary Active Pharmaceutical Ingredient (API) in the manufacture of prescription medications for endometriosis and uterine fibroids.
• Key intermediate in advanced pharmaceutical research and development of novel GnRH antagonist therapies.
• Reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Biochemical research tool for studying gonadotropin-releasing hormone receptor pathways and mechanisms.
• Starting material for the synthesis of related chemical entities in preclinical drug discovery.

Basic Information

Product Name	Elagolix Sodium
CAS No.	832720-36-2
Molecular Formula	C32H29F5N4NaO5
Molecular Weight	667.58 g/mol
Synonyms	Elagolix Sodium Salt; N-[(8R)-5,6-Dihydro-6-oxo-8-(2,4,6-trifluorobenzyl)-2,6-naphthyridin-1(8H)-yl]-4-[[(1R)-2,2,2-trifluoro-1-methylethyl]amino]-3-(trifluoromethyl)benzenesulfonamide Sodium Salt; ABT-620 Sodium; Orilissa (Brand Name API); GnRH Antagonist Elagolix Sodium; 1-[[4-[[(1R)-2,2,2-Trifluoro-1-methylethyl]amino]-3-(trifluoromethyl)phenyl]sulfonyl]-5,6-dihydro-8-(2,4,6-trifluorobenzyl)-6-oxo-2,6-naphthyridin-1(8H)-ide Sodium
EINECS	Contact for details

Quality Control

Our Elagolix Sodium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Chiral Purity	≥99.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.