Description

3-(n-Methylaminocarbonyl)Phenylboronic Acid is a specialized organoboron compound featuring both a boronic acid and an N-methylamide functional group. This bifunctional structure makes it a valuable intermediate in modern synthetic chemistry, particularly for cross-coupling reactions and the development of bioactive molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting proteases and other enzymes.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for forming carbon-carbon bonds with aryl/heteroaryl halides, crucial for creating biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific amide-linked aromatic frameworks.
• Material Science Research: Employed in the development of organic electronic materials, polymers, and metal-organic frameworks (MOFs) where its functional groups enable precise molecular assembly.
• Chemical Biology & Proteomics: Acts as a potential ligand or probe in the study of protein interactions and enzyme inhibition due to its amide and boronic acid motifs.
• Catalyst and Ligand Development: Utilized as a precursor for creating novel catalysts and ligands used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	3-(n-Methylaminocarbonyl)Phenylboronic Acid
CAS No.	832695-88-2
Molecular Formula	C9H12BNO3
Molecular Weight	193.01 g/mol
Synonyms	(3-((Methylcarbamoyl)phenyl)boronic acid; 3-(Methylaminocarbonyl)benzeneboronic acid; m-(N-Methylcarbamoyl)phenylboronic acid; B-[3-[(Methylamino)carbonyl]phenyl]boronic acid; 3-Carbamoylphenylboronic acid N-methyl derivative; 3-Boronobenzamide, N-methyl-; N-Methyl-3-boronobenzamide
EINECS	Contact for details

Quality Control

Our 3-(n-Methylaminocarbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.