Description

n-(3-Dimethylaminopropyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-value, functionalized benzamide derivative containing a pinacol boronate ester group. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in modern synthetic chemistry, particularly for cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors who require precise molecular scaffolds for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronate ester moiety makes it an excellent reagent for forming carbon-carbon bonds, a fundamental step in constructing complex organic molecules.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and the development of novel drug candidates due to its amide linkage and boronic ester functional group.
• Agrochemical Synthesis: Employed as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Utilized in the development of organic electronic materials, polymers, and ligands for catalysis.
• Chemical Biology Probes: Serves as a starting material for synthesizing probes that study biological processes and enzyme functions.

Basic Information

Item	Detail
Product Name	n-(3-Dimethylaminopropyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	832114-10-0
Molecular Formula	C18H29BN2O3
Molecular Weight	332.25 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[3-(dimethylamino)propyl]benzamide; N-[3-(Dimethylamino)propyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 4-Pinacolatoboryl-N-(3-dimethylaminopropyl)benzamide; Benzamide, N-[3-(dimethylamino)propyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 832114-10-0; Boronic acid, B-[4-[[[3-(dimethylamino)propyl]amino]carbonyl]phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our n-(3-Dimethylaminopropyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.