Description

3,5-Dimethylisoxazole-4-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. Its core value lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This reagent is critical for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing novel heterocyclic scaffolds in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research & Development: Used in the synthesis of new herbicide and fungicide molecules with complex isoxazole motifs.
• Material Science & OLED Development: Serves as a precursor for creating advanced organic electronic materials and light-emitting compounds.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds under mild conditions.
• Ligand and Catalyst Design: Utilized in the development of novel bidentate ligands and organometallic catalysts.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes.

Basic Information

Product Name	3,5-Dimethylisoxazole-4-Boronic Acid Pinacol Ester
CAS No.	832114-00-8
Molecular Formula	C11H18BNO3
Molecular Weight	223.08 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-(3,5-dimethylisoxazol-4-yl)-1,3,2-dioxaborolane; 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole; 3,5-Dimethylisoxazole-4-boronic acid pinacol ester; Pinacol 3,5-Dimethylisoxazole-4-boronate; (3,5-Dimethylisoxazol-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3,5-Dimethylisoxazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B) and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full characterization data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.