Description

Thiazole, 4-Methyl-2-[(2R,3R,4S)-4-Methyl-1-Oxaspiro[2.5]Oct-2-Yl]-, Rel- is a high-purity, stereochemically defined organic compound featuring a complex spirocyclic structure fused with a thiazole ring. This compound is of significant interest as a sophisticated chemical intermediate and building block in advanced synthetic chemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex molecular architectures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the thiazole and spirocyclic motifs can contribute to unique biological activity.
• Advanced Material Synthesis: Serves as a precursor for specialized ligands or functional molecules in material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of complex target molecules.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic organic chemistry research.

Basic Information

Product Name	Thiazole, 4-Methyl-2-[(2R,3R,4S)-4-Methyl-1-Oxaspiro[2.5]Oct-2-Yl]-, Rel-
CAS No.	831224-88-5
Molecular Formula	C12H17NOS
Molecular Weight	223.33 g/mol
Synonyms	rel-(2R,3R,4S)-4-Methyl-2-(4-methylthiazol-2-yl)-1-oxaspiro[2.5]octane; 4-Methyl-2-[(2R,3R,4S)-4-methyl-1-oxaspiro[2.5]oct-2-yl]thiazole; (rel)-(2R,3R,4S)-2-(4-Methyl-1,3-thiazol-2-yl)-4-methyl-1-oxaspiro[2.5]octane; Spirocyclic Thiazole Derivative; CAS 831224-88-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and cGMP requirements with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.