Description

4-Ethyl-5-[2-(4-Methylphenyl)Cyclopropyl]-4H-1,2,4-Triazole-3-Thiol is a specialized heterocyclic compound featuring a unique cyclopropyl-linked triazole-thiol structure. This molecular architecture makes it a valuable advanced intermediate for the research and development of novel active ingredients in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists working on new drug candidates, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or metabolic conditions.
• Agrochemical Research: Used in the development of new-generation fungicides, herbicides, or plant growth regulators, leveraging its heterocyclic core for biological activity.
• Ligand Synthesis: The thiol and triazole groups make it a suitable precursor for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in academic and industrial research to develop molecular probes for studying enzyme function or protein interactions.
• Advanced Material Development: Acts as a monomer or functional additive in the synthesis of polymers with specific electronic or thermal properties.

Basic Information

Product Name	4-Ethyl-5-[2-(4-Methylphenyl)Cyclopropyl]-4H-1,2,4-Triazole-3-Thiol
CAS No.	828280-55-3
Molecular Formula	C14H17N3S
Molecular Weight	259.37 g/mol
Synonyms	4-Ethyl-5-(2-p-tolylcyclopropyl)-4H-1,2,4-triazole-3-thiol; 4H-1,2,4-Triazole-3-thiol, 4-ethyl-5-[2-(4-methylphenyl)cyclopropyl]-; 5-(2-(4-Methylphenyl)cyclopropyl)-4-ethyl-4H-1,2,4-triazole-3-thiol; 4-Ethyl-5-(2-(p-tolyl)cyclopropyl)-1,2,4-triazole-3-thiol; 828280-55-3
EINECS	Contact for details

Quality Control

Our production of 4-Ethyl-5-[2-(4-Methylphenyl)Cyclopropyl]-4H-1,2,4-Triazole-3-Thiol adheres to strict internal quality protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques like HPLC, GC, and NMR to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full transparency and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when handling opened containers to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.