Description

1-Bromo-2-Ethenyl-4-Fluorobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, combining bromine, fluorine, and a vinyl group to enable precise cross-coupling reactions and serve as a versatile precursor. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Heck coupling reactions to construct complex biaryl and conjugated systems.
• Chemical Research & Development: Employed in academic and industrial labs for method development, exploring new reaction pathways, and synthesizing complex molecular libraries.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the electronic effects of fluorine substitution in aromatic systems and its influence on reaction kinetics.

Basic Information

Product Name	1-Bromo-2-Ethenyl-4-Fluorobenzene
CAS No.	828267-47-6
Molecular Formula	C8H6BrF
Molecular Weight	201.04 g/mol
Synonyms	2-Bromo-1-Ethenyl-4-Fluorobenzene; 4-Fluoro-2-Vinylbromobenzene; 2-Vinyl-4-Fluorobromobenzene; 1-Bromo-2-Vinyl-4-Fluorobenzene; (2-Bromo-5-fluorophenyl)ethene; 828267-47-6; 5-Fluoro-2-vinylbromobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2-Ethenyl-4-Fluorobenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.