Description

1-Propyl-1H-Pyrazole-4-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly for developing new active ingredients and functional molecules. The CAS number for this product is 827614-69-7.

Application

This versatile boronic ester is a key reagent in several high-value industrial and research applications:

• Pharmaceutical Intermediates: A crucial building block in Suzuki-Miyaura cross-couplings for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific pyrazole-based structures.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, including ligands for catalysts and components in light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for diagnostic and research purposes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CROs/CMOs producing specialized fine chemicals for clients.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Item	Detail
Product Name	1-Propyl-1H-Pyrazole-4-Boronic Acid Pinacol Ester
CAS No.	827614-69-7
Molecular Formula	C₁₃H₂₃BN₂O₂
Molecular Weight	250.15 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-propyl-1H-pyrazole; 1-Propyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Propyl-1H-pyrazole-4-boronic acid pinacol ester; 1-Propyl-4-(pinacolboranyl)-1H-pyrazole; Pyrazole-4-boronic acid pinacol ester, 1-propyl-; 827614-69-7; Boric acid, B-(1-propyl-1H-pyrazol-4-yl)-, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Propyl-1H-Pyrazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP-intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.