Description

4-(n-Cyclopropylaminocarbonyl)Phenylboronic Acid, Pinacol Ester is a sophisticated boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in its role as a protected boronic acid, offering enhanced stability and solubility for use in sensitive cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in constructing complex heterocyclic and biaryl structures found in advanced crop protection agents.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials and polymers.
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and inhibitors for biological target identification.
• Catalyst & Ligand Development: Acts as a starting material for creating novel bidentate ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-(n-Cyclopropylaminocarbonyl)Phenylboronic Acid, Pinacol Ester
CAS No.	827614-68-6
Molecular Formula	C16H22BNO3
Molecular Weight	287.17 g/mol
Synonyms	4-(Cyclopropylcarbamoyl)phenylboronic acid pinacol ester; [4-(N-Cyclopropylaminocarbonyl)phenyl]boronic acid pinacol ester; 4-(Cyclopropylcarbamoyl)benzeneboronic acid pinacol ester; B-[4-(Cyclopropylaminocarbonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Cyclopropylaminocarbonylphenylboronic Acid Pinacol Ester; CPAPB Pinacol Ester; (4-(Cyclopropylcarbamoyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(n-Cyclopropylaminocarbonyl)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees batch-to-batch consistency and traceability for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent hydrolysis and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.