Description

1,3,2-Dioxaborinane, 2-(4-Chlorophenyl)-5,5-Dimethyl- is a specialized organoboron compound featuring a cyclic dioxaborinane core with a chlorophenyl substituent. This structure makes it a valuable synthetic intermediate and building block in advanced organic synthesis, particularly for constructing complex molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a precursor to active pharmaceutical ingredients (APIs).

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common motif in pharmaceuticals and organic materials.
• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific chlorinated aromatic structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where boron-containing compounds can modulate electronic properties.
• Ligand and Catalyst Development: Acts as a precursor for creating novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	1,3,2-Dioxaborinane, 2-(4-Chlorophenyl)-5,5-Dimethyl-
CAS No.	827605-29-8
Molecular Formula	C11H14BClO2
Molecular Weight	224.49 g/mol
Synonyms	2-(4-Chlorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 5,5-Dimethyl-2-(4-chlorophenyl)-1,3,2-dioxaborinane; 4-Chlorophenylboronic acid neopentyl glycol ester; (4-Chlorophenyl)boronic acid neopentyl ester; 2-(p-Chlorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Chloro-benzeneboronic acid neopentyl glycol ester; p-Chlorophenylboronic acid neopentyl glycol ester; 4-Chlorophenyl-B-neopentyl glycol ester
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborinane, 2-(4-Chlorophenyl)-5,5-Dimethyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards where applicable, supporting our commitment to supply reliability and technical excellence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.