Description

Methanone, [(2R)-3,6-Dihydro-4,5-Dimethyl-2H-Pyran-2-Yl](4-Methylphenyl)- (9Ci) is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and unique molecular scaffold, which are critical for constructing complex molecules with high specificity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in drug discovery, process chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where specific stereochemistry can influence biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the study and development of new asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Institutional Research: A valuable tool for synthetic organic chemists in universities and research institutes exploring new reaction methodologies and compound libraries.
• Material Science Precursor: Potential use as a monomer or building block for novel polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	Methanone, [(2R)-3,6-Dihydro-4,5-Dimethyl-2H-Pyran-2-Yl](4-Methylphenyl)- (9Ci)
CAS No.	827337-19-9
Molecular Formula	C15H18O2
Molecular Weight	230.30 g/mol
Synonyms	(R)-4,5-Dimethyl-3,6-dihydro-2H-pyran-2-yl(4-methylphenyl)methanone; (2R)-4,5-Dimethyl-3,6-dihydro-2H-pyran-2-yl(4-tolyl)methanone; (R)-2-(4-Methylbenzoyl)-4,5-dimethyl-3,6-dihydro-2H-pyran; p-Tolyl (R)-4,5-dimethyl-5,6-dihydro-2H-pyran-2-yl ketone; (R)-4,5-Dimethyl-2-(4-methylbenzoyl)-3,6-dihydro-2H-pyran; 827337-19-9; (2R)-3,6-Dihydro-4,5-dimethyl-2H-pyran-2-yl(4-methylphenyl)methanone
EINECS	Contact for details

Quality Control

Our production of Methanone, [(2R)-3,6-Dihydro-4,5-Dimethyl-2H-Pyran-2-Yl](4-Methylphenyl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.