Description

n-[4-(1H,1H,2H,2H-Perfluorohexyl)Benzyloxycarbonyloxy]Succinimide is a specialized fluorinated active ester reagent designed for the selective modification of biomolecules and polymers. This compound matters for its unique ability to introduce a highly hydrophobic and oleophobic perfluoroalkyl chain, imparting properties like extreme chemical resistance, low surface energy, and thermal stability to target materials. It is primarily needed by researchers and manufacturers in advanced material science, pharmaceuticals, and specialty coatings for creating high-performance, functionalized surfaces and conjugates.

Application

• Bioconjugation Reagent: For the site-specific labeling of peptides, proteins, and antibodies with fluorinated tags to alter solubility, stability, or for tracking purposes.
• Polymer Functionalization: Used to graft perfluoroalkyl groups onto polymer backbones (e.g., polyethyleneimine, polysaccharides) to create materials with tailored surface properties for non-stick or anti-fouling applications.
• Surface Modification Agent: Key in developing self-assembled monolayers (SAMs) or coatings on glass, metals, and semiconductors to achieve superhydrophobic and oleophobic surfaces.
• Intermediate for Fluorinated Materials: Serves as a critical building block in the synthesis of more complex fluorinated surfactants, liquid crystals, and pharmaceutical intermediates.
• Proteomics Research: Employed in chemical proteomics for activity-based protein profiling (ABPP) to study enzyme function using fluorinated probes.
• Diagnostic Assay Development: Facilitates the creation of stable, non-interfering fluorinated linkers in biosensors and diagnostic kits.

Basic Information

Product Name	n-[4-(1H,1H,2H,2H-Perfluorohexyl)Benzyloxycarbonyloxy]Succinimide
CAS No.	825635-46-9
Molecular Formula	C18H11F13N2O5
Molecular Weight	582.28 g/mol
Synonyms	4-(1H,1H,2H,2H-Perfluorohexyl)benzyl N-succinimidyl carbonate; N-Succinimidyl 4-(perfluorohexyl)benzyl carbonate; PFHBC-OSu; 1-{[4-(1H,1H,2H,2H-Perfluorohexyl)benzyl]oxycarbonyloxy}-2,5-pyrrolidinedione; Fluorinated NHS ester; Perfluorohexylbenzyloxycarbonyloxysuccinimide; F13Bz-OSu; (Perfluorohexyl)benzyl N-oxysuccinimidyl carbonate
EINECS	Contact for details

Quality Control

Our n-[4-(1H,1H,2H,2H-Perfluorohexyl)Benzyloxycarbonyloxy]Succinimide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach ambient temperature before opening to minimize moisture condensation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.