Description

2-Chloro-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide is a high-value, synthetically versatile boronic ester derivative. This compound serves as a critical building block in modern organic synthesis, particularly for cross-coupling reactions that form carbon-carbon bonds. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boronic acid pinacol ester precursor for constructing biaryl and heterobiaryl scaffolds prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of complex molecules targeting various therapeutic areas, including oncology and central nervous system disorders.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology & Proteomics: Can be utilized in the development of activity-based probes and bioconjugation reagents.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries for biological evaluation.

Basic Information

Item	Detail
Product Name	2-Chloro-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide
CAS No.	825630-79-3
Molecular Formula	C14H19BClNO3
Molecular Weight	295.57 g/mol
Synonyms	2-Chloro-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide; 4-(2-Chloroacetamido)phenylboronic acid pinacol ester; N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-chloroacetamide; 2-Chloroacetamide, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 825630-79-3; BRN 9087555
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening a new container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.