Description

1,3-Dioxolane-4,5-dicarboxylic Acid, 2,2-Dimethyl-, 4-Ethyl Ester, (4S,5S)- is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined dioxolane structure, which serves as a key precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral catalysts, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the asymmetric synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for metal-catalyzed reactions, enhancing enantioselectivity.
• Fine Chemical Synthesis: Serves as a building block for creating complex natural products, flavors, and fragrances requiring specific stereochemistry.
• Material Science Research: Employed in the synthesis of specialized polymers and advanced organic materials with tailored properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and stereochemistry.

Basic Information

Item	Details
Product Name	1,3-Dioxolane-4,5-dicarboxylic Acid, 2,2-Dimethyl-, 4-Ethyl Ester, (4S,5S)-
CAS No.	824985-33-3
Molecular Formula	C10H16O6
Molecular Weight	232.23 g/mol
Synonyms	(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylic acid 4-ethyl ester; (4S,5S)-4-Ethoxycarbonyl-2,2-dimethyl-1,3-dioxolane-5-carboxylic acid; (4S-cis)-4-(Ethoxycarbonyl)-2,2-dimethyl-1,3-dioxolane-5-carboxylic Acid; Ethyl (4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate; Chiral Dioxolane Diester; (S,S)-Dioxolane Derivative
EINECS	Contact for details

Quality Control

Our production of 1,3-Dioxolane-4,5-dicarboxylic Acid, 2,2-Dimethyl-, 4-Ethyl Ester, (4S,5S)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.