Description

n-[3,5-Bis(Trifluoromethyl)Phenyl]-n-(1,1-Dioxido-1,2-Benzisothiazol-3-Yl)Amine is a high-value, specialized organic intermediate featuring a unique trifluoromethylphenyl and benzisothiazole sulfonamide scaffold. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where its structure imparts desirable properties like metabolic stability and enhanced bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry, particularly those working on kinase inhibitors, anti-inflammatory agents, and novel therapeutic small molecules. Its precise chemical architecture makes it an indispensable reagent for constructing complex molecular targets.

Application

• Pharmaceutical Intermediate: Key synthon for the development of protein kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Building block for novel herbicides and fungicides, leveraging the biological activity of the benzisothiazole moiety.
• Material Science: Potential monomer or additive for specialty polymers where fluorine content enhances chemical resistance and surface properties.
• Organic Synthesis: Versatile reagent for constructing complex aromatic amines and sulfonamides in academic and industrial research.
• Bioconjugation Chemistry: The amine and sulfonamide groups offer handles for linking to other molecules or surfaces in probe development.

Basic Information

Product Name	n-[3,5-Bis(Trifluoromethyl)Phenyl]-n-(1,1-Dioxido-1,2-Benzisothiazol-3-Yl)Amine
CAS No.	823830-85-9
Molecular Formula	C16H9F6N2O2S
Molecular Weight	407.31 g/mol
Synonyms	3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-1,2-benzisothiazole 1,1-Dioxide; N-(3,5-Bis(trifluoromethyl)phenyl)-1,2-benzisothiazol-3-amine 1,1-Dioxide; 1,2-Benzisothiazol-3-amine, N-[3,5-bis(trifluoromethyl)phenyl]-, 1,1-dioxide; 823830-85-9; Amine, n-[3,5-bis(trifluoromethyl)phenyl]-n-(1,1-dioxido-1,2-benzisothiazol-3-yl)-; BBTAB; 3-Amino-1,2-benzisothiazole 1,1-dioxide derivative
EINECS	Contact for details

Quality Control

Our n-[3,5-Bis(Trifluoromethyl)Phenyl]-n-(1,1-Dioxido-1,2-Benzisothiazol-3-Yl)Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.