Description

Dichloro[(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Di(3,5-Xylyl)Phosphino)-3,3'-Bipyridine][(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium (II), Min. 95 is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and other critical synthetic transformations. It is essential for R&D chemists and process engineers in the pharmaceutical and fine chemical industries who require high enantiomeric purity and consistent catalytic performance in the synthesis of complex chiral molecules.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral ketones, imines, and olefins in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate Synthesis: Key for producing active pharmaceutical ingredients (APIs) with high optical purity, such as chiral amines and alcohols.
• Fine Chemical Manufacturing: Enables the production of high-value specialty chemicals, flavors, and fragrances with specific stereochemistry.
• Academic and Industrial R&D: A valuable tool for developing new catalytic methodologies and exploring novel synthetic routes.
• Process Chemistry Optimization: Used to scale up and optimize catalytic processes for cost-effective and sustainable manufacturing.

Basic Information

Product Name	Dichloro[(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Di(3,5-Xylyl)Phosphino)-3,3'-Bipyridine][(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium (II), Min. 95
CAS No.	821793-37-7
Molecular Formula	C70H72Cl2N4O4P2Ru
Molecular Weight	1245.15 g/mol (approx.)
Synonyms	(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di-3,5-xylylphosphino)-3,3'-bipyridine (1S,2S)-(-)-1,2-diphenylethylenediamine ruthenium(II) dichloride; Ru-Mandyphos SL-M002-1 catalyst; Mandyphos SL-M002-1 Ru complex; Chiral Ru(II) Mandyphos complex; Asymmetric hydrogenation catalyst Ru-M002-1; [RuCl2((S)-Mandyphos)((S,S)-DPEN)]; Ruthenium(II) dichloride (S)-Mandyphos (S,S)-DPEN complex
EINECS	Contact for details

Quality Control

Our high-purity chiral catalyst is manufactured under controlled conditions to ensure batch-to-batch consistency and optimal catalytic activity. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral assay, to verify compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral integrity is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 95.0%
Chiral Purity	Min. 99.0% ee
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.