Description

Dichloro[(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Diphenylphosphino)-3,3'-Bipyridine][(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium (II) is a high-purity, chiral ruthenium complex designed for advanced asymmetric synthesis. This compound matters as a highly selective and efficient catalyst, enabling the production of enantiomerically pure intermediates critical for pharmaceuticals and fine chemicals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-performance catalysts for complex transformations.

Application

• Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of ketones, imines, and olefins to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key for constructing stereogenic centers in active pharmaceutical ingredients (APIs), including those for cardiovascular, CNS, and antiviral drugs.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the scalable production of enantiopure flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new catalytic pathways in organic synthesis.
• Process Chemistry Optimization: Employed to develop more efficient, sustainable, and cost-effective manufacturing routes for complex molecules.

Basic Information

Item	Detail
Product Name	Dichloro[(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Diphenylphosphino)-3,3'-Bipyridine][(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium (II)
CAS No.	821793-36-6
Molecular Formula	C58H56Cl2N4O4P2Ru
Molecular Weight	1084.98 g/mol
Synonyms	Ru-MsDPEN Catalyst; (S,S)-Ru-MsDPEN; Dichloro[(S)-(-)-2,2',6,6'-tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium; Ruthenium(II) (S,S)-MsDPEN complex; Asymmetric Hydrogenation Catalyst Ru-MsDPEN; [RuCl2((S)-MsDPEN)((S,S)-DPEN)]; Noyori-type Ru catalyst with MsDPEN ligand
EINECS	Contact for details

Quality Control

Every batch of our Dichloro[(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Diphenylphosphino)-3,3'-Bipyridine][(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium (II) is manufactured and tested under strict quality management systems. We guarantee a minimum purity of 95% (by HPLC), with comprehensive testing for identity, potency, and chiral purity. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	Min. 95.0%
Chiral Purity (HPLC)	Min. 99.0% e.e.
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals (ICP-MS)	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.