Description

1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-3-(m-Tolyl)Urea is a high-purity, functionalized boronic ester derivative that serves as a critical building block in modern synthetic chemistry. This compound is valued for its role as a versatile intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery, agrochemical development, and advanced materials science.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by facilitating the creation of complex aryl-aryl bonds.
• Material Science: Building block for organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of probes and inhibitors for studying enzyme function and protein-protein interactions.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research within university and CRO laboratories.
• Custom Synthesis: Serves as a starting point for the contract manufacturing of specialty fine chemicals and custom-designed molecules.

Basic Information

Product Name	1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-3-(m-Tolyl)Urea
CAS No.	819056-45-6
Molecular Formula	C20H25BN2O3
Molecular Weight	352.24 g/mol
Synonyms	1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-(3-methylphenyl)urea; 3-Methylphenyl-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-urea; m-Tolyl-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl]-urea; B-[3-[[(3-Methylphenyl)amino]carbonyl]amino]phenyl]boronic acid, pinacol ester; Urea, N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N'-(3-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-3-(m-Tolyl)Urea is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.