Description

tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylmethylcarbamate is a high-purity, protected boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic coupling steps.
• Material Science: Employed in the creation of organic electronic materials, such as polymers for OLEDs and OFETs, where precise molecular architecture is crucial.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and enzyme inhibitors.
• Academic & Industrial R&D: A staple reagent in laboratory-scale research for method development and the construction of complex organic libraries.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized phosphine or N-heterocyclic carbene ligands used in catalysis.

Basic Information

Product Name	tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylmethylcarbamate
CAS No.	817618-31-8
Molecular Formula	C19H30BNO4
Molecular Weight	347.26 g/mol
Synonyms	3-((((tert-Butoxy)carbonyl)(methyl)amino)methyl)phenylboronic acid pinacol ester; tert-Butyl N-methyl-N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]carbamate; BOC-Protected 3-(Pinacolboronato)benzylmethylamine; N-BOC-N-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylamine; 3-(N-BOC-N-Methylaminomethyl)phenylboronic Acid Pinacol Ester; 817618-31-8; (3-((((tert-Butoxy)carbonyl)(methyl)amino)methyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylmethylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH, TSCA, and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and prevent hydrolysis. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.