Description

Glycine, n-[[[(1R,2S)-2-Methylcyclohexyl]oxy]carbonyl]-, Methyl Ester, Rel- is a specialized chiral glycine derivative, a high-value building block designed for advanced organic synthesis. Its core value lies in the precise stereochemistry and protected functional groups, which are critical for constructing complex molecules with defined three-dimensional structures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical purity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, especially for central nervous system (CNS) and antiviral drug candidates.
• Peptidomimetics Research: Used to introduce constrained, non-natural amino acid motifs into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for developing novel chiral ligands and organocatalysts.
• Agrochemical Synthesis: Employed in the research and development of enantiomerically pure herbicides and fungicides.
• Chemical Biology Probes: Utilized to create labeled or modified amino acid analogs for studying enzyme mechanisms and protein interactions.
• Fine Chemical Production: Acts as a building block for specialty chemicals requiring high stereochemical fidelity.

Basic Information

Product Name	Glycine, n-[[[(1R,2S)-2-Methylcyclohexyl]oxy]carbonyl]-, Methyl Ester, Rel-
CAS No.	817554-06-6
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	rel-(1R,2S)-2-Methylcyclohexyl N-(Methoxycarbonyl)glycinate; Methyl N-[[(1R,2S)-2-methylcyclohexyl]oxy]carbonyl]glycinate; Glycine, N-[(1R,2S)-2-methylcyclohexyloxycarbonyl]-, methyl ester; N-(((1R,2S)-2-Methylcyclohexyloxy)carbonyl)glycine methyl ester; Chiral Glycine Ester Derivative; Protected Glycine Methyl Ester
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral GC/HPLC, and NMR to confirm identity, chemical purity, and stereochemical integrity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.