Description

2-[(2,2,6,6-Tetramethyl-1-Piperidyl)Methyl]Phenylboronic Acid is a specialized boronic acid derivative featuring a sterically hindered TEMPO-analogous amine moiety, making it a valuable building block in advanced organic synthesis. This compound is particularly significant for its dual functionality, serving as both a protected amine precursor and a Suzuki-Miyaura cross-coupling partner. It is essential for research and development chemists in the pharmaceutical and agrochemical industries who require high-purity, functionalized intermediates for creating complex molecules, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those requiring sterically hindered amine or nitroxyl radical functionalities.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its unique structure for bioactivity.
• Polymer Chemistry: Serves as a functional monomer or chain-transfer agent in the development of specialty polymers with controlled radical polymerization techniques.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and molecular sensors.
• Cross-Coupling Reactions: Acts as a boronic acid partner in Suzuki-Miyaura cross-coupling reactions to form biaryl and other carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	2-[(2,2,6,6-Tetramethyl-1-Piperidyl)Methyl]Phenylboronic Acid
CAS No.	815581-79-4
Molecular Formula	C16H26BNO2
Molecular Weight	275.20 g/mol
Synonyms	2-[(2,2,6,6-Tetramethylpiperidin-1-yl)methyl]phenylboronic Acid; (2-((2,2,6,6-Tetramethylpiperidin-1-yl)methyl)phenyl)boronic Acid; 2-((2,2,6,6-Tetramethyl-1-piperidinyl)methyl)benzeneboronic Acid; 2-(TEMPO-methyl)phenylboronic Acid; B-(2-((2,2,6,6-Tetramethyl-1-piperidinyl)methyl)phenyl)boronic Acid; 815581-79-4; Boronic acid, B-[2-[(2,2,6,6-tetramethyl-1-piperidinyl)methyl]phenyl]-
EINECS	Contact for details

Quality Control

Our 2-[(2,2,6,6-Tetramethyl-1-Piperidyl)Methyl]Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.