Description

4-Amino-3,5-Difluoroacetophenone is a high-purity, fluorinated aromatic ketone derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a difluoro substitution pattern, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced thermal and chemical resistance.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating novel fluorinated compounds.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	4-Amino-3,5-Difluoroacetophenone
CAS No.	811799-69-6
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	1-(4-Amino-3,5-difluorophenyl)ethanone; 3',5'-Difluoro-4'-aminoacetophenone; 4-Acetylamino-3,5-difluorobenzene; 4-Amino-3,5-difluoroacetophenone; 811799-69-6; Ethanone, 1-(4-amino-3,5-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4-Amino-3,5-Difluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and oxidizable nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.