Description

1,3-Cyclohexanediol,6-(3-Hydroxy-1-Butenylidene)-1,5,5-Trimethyl-,(1R,3S,6S)-(9Ci) is a high-purity, stereochemically defined organic compound with the CAS number 809281-50-3. This specialized diol derivative is valued for its unique molecular scaffold, which serves as a critical chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Synthesis: Used in the production of advanced, high-efficacy crop protection agents and pesticides.
• Fine Chemical Production: Serves as a versatile building block for synthesizing complex fragrances, flavors, and specialty chemicals.
• Academic & Industrial Research: A valuable reagent in methodological chemistry research, catalysis studies, and process development.
• Material Science Precursor: Potential use in the synthesis of specialized polymers, ligands, or advanced organic materials.

Basic Information

Item	Details
Product Name	1,3-Cyclohexanediol,6-(3-Hydroxy-1-Butenylidene)-1,5,5-Trimethyl-,(1R,3S,6S)-(9Ci)
CAS No.	809281-50-3
Molecular Formula	C13H22O3
Molecular Weight	226.31 g/mol
Synonyms	(1R,3S,6S)-6-[(E)-3-Hydroxybut-1-en-1-yl]-1,5,5-trimethylcyclohexane-1,3-diol; (1R,3S,6S)-6-(3-Hydroxy-1-butenylidene)-1,5,5-trimethyl-1,3-cyclohexanediol; Ambretone; (E)-6-(3-Hydroxybut-1-en-1-yl)-1,5,5-trimethylcyclohexane-1,3-diol; (1R,3S,6S)-Ambretone; A key intermediate for Ambrox®.
EINECS	Contact for details

Quality Control

Every batch of 1,3-Cyclohexanediol,6-(3-Hydroxy-1-Butenylidene)-1,5,5-Trimethyl-,(1R,3S,6S)-(9Ci) is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, GC, NMR, and optical rotation measurements. Our quality commitment supports applications requiring high-purity chiral intermediates for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.