Description

2-(3,5-Difluorophenyl)Malondialdehyde is a specialized fluorinated malondialdehyde derivative, a key reactive dialdehyde intermediate in advanced organic synthesis. This compound is valued for its unique bifunctional reactivity, enabling its use as a versatile building block for constructing complex heterocyclic and pharmaceutical scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated heterocycles like pyrimidines and pyridines.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluorophenyl moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of novel polymers, dendrimers, and organic electronic materials due to its reactive aldehyde groups.
• Chemical Biology Probes: Useful for synthesizing fluorescent probes or affinity tags that target specific biological structures.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-(3,5-Difluorophenyl)Malondialdehyde
CAS No.	808764-39-8
Molecular Formula	C9H6F2O2
Molecular Weight	184.14 g/mol
Synonyms	3,5-Difluorophenylmalondialdehyde; 2-(3,5-Difluorophenyl)-1,3-propanedial; Malondialdehyde, 2-(3,5-difluorophenyl)-; 1,3-Propanedial, 2-(3,5-difluorophenyl)-; (3,5-Difluorophenyl)propanedial
EINECS	Contact for details

Quality Control

Our 2-(3,5-Difluorophenyl)Malondialdehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.