Description

(R)-2-(Oxetan-2-Yl)Ethan-1-Ol is a high-purity chiral building block featuring an oxetane ring, a valuable structural motif in modern medicinal chemistry. This compound is essential for the synthesis of complex, biologically active molecules, offering a unique three-dimensional scaffold to modulate physicochemical and pharmacokinetic properties. It is primarily utilized by pharmaceutical R&D and process chemistry teams in the development of new therapeutic agents, including small molecule drugs and targeted therapies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Proteolysis Targeting Chimera (PROTAC) Synthesis: Used as a linker or component to construct bifunctional molecules for targeted protein degradation.
• Peptidomimetic Chemistry: Incorporation into peptide analogs to enhance metabolic stability and membrane permeability.
• Asymmetric Synthesis: Serves as a chiral starting material or auxiliary in stereoselective chemical transformations.
• Material Science Research: Potential monomer for creating novel polymers with specific rigidity and functionality.
• Chemical Biology Probes: Building block for the development of tool compounds used to study biological pathways.

Basic Information

Product Name	(R)-2-(Oxetan-2-Yl)Ethan-1-Ol
CAS No.	808172-41-0
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	(R)-2-(Oxetan-2-yl)ethanol; (2R)-2-(Oxetan-2-yl)ethan-1-ol; (R)-2-Oxetaneethanol; (R)-Oxetane-2-ethanol; (R)-2-(2-Oxetanyl)ethanol; (R)-β-Hydroxyethyloxetane; (R)-2-Oxetan-2-ylethanol
EINECS	Contact for details

Quality Control

Our (R)-2-(Oxetan-2-Yl)Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.