Description

4,4,5,5-Tetramethyl-2-(3-Methylbutan-2-Yl)-1,3,2-Dioxaborolane is a high-purity, sterically hindered boronic ester derivative, a crucial intermediate in modern synthetic chemistry. Its primary value lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating advanced organic electronic materials and emissive layers.
• Ligand and Catalyst Development: Employed in the preparation of novel boron-containing ligands and organometallic catalysts.
• Polymer Chemistry: Facilitates the synthesis of specialty polymers and functional materials with tailored properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and molecular architectures.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(3-Methylbutan-2-Yl)-1,3,2-Dioxaborolane
CAS No.	807611-14-9
Molecular Formula	C₁₃H₂₇BO₂
Molecular Weight	226.17 g/mol
Synonyms	2-(3-Methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3-methylbutan-2-yl)boronate; (3-Methylbutan-2-yl)boronic acid pinacol ester; sec-Isoamylboronic acid pinacol ester; 1,1,2-Trimethylpropylboronic acid pinacol ester; (1,1,2-Trimethylpropyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 4,4,5,5-Tetramethyl-2-(3-Methylbutan-2-Yl)-1,3,2-Dioxaborolane is produced under strict quality management protocols. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including NMR, GC, and HPLC. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.