Description

4,7-Ethano-1H-Isoindole-1-Carboxylic Acid, Octahydro-2-Methyl-, (1R,3As,7Ar)-Rel- is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required for efficacy and safety. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of proprietary drug candidates and complex APIs.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel heterocyclic compounds and exploring new chemical spaces.
• Asymmetric Catalysis Studies: Serves as a chiral template or ligand precursor in the development of stereoselective synthetic methodologies.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	4,7-Ethano-1H-Isoindole-1-Carboxylic Acid, Octahydro-2-Methyl-, (1R,3As,7Ar)-Rel-
CAS No.	807311-21-3
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	rel-(1R,3aS,7aR)-Octahydro-2-methyl-4,7-ethano-1H-isoindole-1-carboxylic acid; (1R,3aS,7aR)-rel-2-Methyloctahydro-4,7-ethano-1H-isoindole-1-carboxylic acid; Octahydro-2-methyl-4,7-ethano-1H-isoindole-1-carboxylic acid, (1R,3aS,7aR)-rel-; 807311-21-3; 4,7-Ethano-1H-isoindole-1-carboxylic acid, octahydro-2-methyl-, (1R,3aS,7aR)-rel-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Production follows cGMP (current Good Manufacturing Practice) guidelines where applicable, and comprehensive analytical characterization is performed using HPLC, GC, NMR, and MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.