Description

Propiophenone, 2-Amino-2-(Trifluoromethyl)- (8Ci) is a specialized trifluoromethylated chiral building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, combining an amino group with a trifluoromethyl group on a propiophenone backbone, which is highly valuable for modulating the physicochemical properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a building block for specialty polymers and advanced organic materials with tailored properties.
• Fluorine Chemistry Studies: An important compound for academic and industrial research into the synthesis and behavior of fluorinated organic molecules.

Basic Information

Product Name	Propiophenone, 2-Amino-2-(Trifluoromethyl)- (8Ci)
CAS No.	803612-83-1
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	2-Amino-2-(trifluoromethyl)propiophenone; 1-Phenyl-2-amino-2-(trifluoromethyl)-1-propanone; α-Amino-α-(trifluoromethyl)propiophenone; 2-Amino-2-(trifluoromethyl)-1-phenylpropan-1-one; 2-Amino-2-(trifluoromethyl)-1-phenyl-1-propanone; (RS)-2-Amino-2-(trifluoromethyl)propiophenone; (±)-2-Amino-2-(trifluoromethyl)propiophenone
EINECS	Contact for details

Quality Control

Our Propiophenone, 2-Amino-2-(Trifluoromethyl)- (8Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the exacting standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.