Description

Ketone, Methyl 3-Methyl-4-Phenyl-4-Piperidyl, trans-(- (8Ci) is a specialized piperidine-derived ketone compound of significant interest in advanced organic synthesis. This high-purity intermediate is valued for its defined stereochemistry and structural framework, which are critical for constructing complex molecules. It is primarily sought after by research institutions and pharmaceutical development teams for use as a key building block in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and analgesic drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its defined stereogenic center and functional groups.
• Organic Synthesis: Serves as a versatile precursor for synthesizing more complex nitrogen-containing heterocycles and fine chemicals.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Academic & Industrial R&D: Utilized in exploratory chemistry for developing novel synthetic methodologies and catalysts.

Basic Information

Product Name	Ketone, Methyl 3-Methyl-4-Phenyl-4-Piperidyl, trans-(- (8Ci)
CAS No.	802569-61-5
Molecular Formula	C13H17NO
Molecular Weight	203.28 g/mol
Synonyms	trans-(-)-Methyl 3-methyl-4-phenyl-4-piperidyl ketone; (3R,4R)-3-Methyl-4-phenyl-4-piperidinyl methyl ketone; 1-[(-)-(3R,4R)-3-Methyl-4-phenyl-4-piperidyl]ethanone; 4-Piperidinyl methyl ketone, 3-methyl-4-phenyl-, trans-(-)-; 802569-61-5; Methyl (3R,4R)-3-methyl-4-phenylpiperidin-4-yl ketone
EINECS	Contact for details

Quality Control

Our Ketone, Methyl 3-Methyl-4-Phenyl-4-Piperidyl, trans-(- (8Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.