Description

3H-Diazirine,3-[2-(Benzylmethylamino)Ethyl]-3-Methyl-(8Ci) is a specialized diazirine derivative, a class of compounds valued for their ability to generate highly reactive carbenes upon photolysis. This compound is a critical photoaffinity labeling reagent, enabling the study of biomolecular interactions and the mapping of binding sites in drug discovery and biochemical research. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in proteomics and chemical biology.

Application

• Photoaffinity Labeling (PAL): A key reagent for covalent cross-linking to probe protein-ligand, protein-protein, and protein-nucleic acid interactions.
• Chemical Biology & Proteomics: Used to identify and characterize unknown biological targets and binding pockets for drug candidates.
• Bioconjugation: Facilitates the site-specific attachment of probes, tags, or drugs to biomolecules under mild, light-activated conditions.
• Materials Science Research: Employed in surface modification and polymer cross-linking studies to create novel functional materials.
• Metabolic Pathway Analysis: Serves as a tool to track and analyze small molecule metabolites within complex biological systems.

Basic Information

Product Name	3H-Diazirine,3-[2-(Benzylmethylamino)Ethyl]-3-Methyl-(8Ci)
CAS No.	801204-59-1
Molecular Formula	C13H19N3
Molecular Weight	217.31 g/mol
Synonyms	3-[2-(Benzylmethylamino)ethyl]-3-methyl-3H-diazirine; 3-Methyl-3-[2-(N-methyl-N-benzylamino)ethyl]diazirine; N-Benzyl-N-methyl-2-(3-methyl-3H-diazirin-3-yl)ethanamine; Benzylmethyl[2-(3-methyl-3H-diazirin-3-yl)ethyl]amine; Photoaffinity Labeling Reagent; Diazirine Crosslinker
EINECS	Contact for details

Quality Control

Every batch of our 3H-Diazirine,3-[2-(Benzylmethylamino)Ethyl]-3-Methyl-(8Ci) is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, critical for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems are designed to support research requiring reliable and reproducible performance in photoaffinity labeling experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; handle under an inert atmosphere when possible and minimize exposure to ambient conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.