Description

1-Bromo-2-Iodo-4,5-Dimethoxybenzene is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents on a dimethoxybenzene core, makes it a versatile precursor for constructing complex molecules via selective cross-coupling reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require halogenated aromatic scaffolds.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating advanced organic electronic materials and liquid crystal compounds.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing tagged molecules for studying biological pathways and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects.

Basic Information

Product Name	1-Bromo-2-Iodo-4,5-Dimethoxybenzene
CAS No.	89978-46-1
Molecular Formula	C8H8BrIO2
Molecular Weight	342.96 g/mol
Synonyms	2-Bromo-1-Iodo-4,5-Dimethoxybenzene; 4,5-Dimethoxy-1-bromo-2-iodobenzene; Benzene, 1-bromo-2-iodo-4,5-dimethoxy-; 1-Bromo-2-iodo-4,5-dimethoxy-benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Iodo-4,5-Dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.