Description

Cyclobutanecarboxylic Acid, 3-(Methylthio)-, Methyl Ester, cis- (9Ci) is a specialized chiral building block featuring a cyclobutane ring system functionalized with a methylthio group and a methyl ester. This compound matters as a high-value intermediate for the synthesis of complex molecules, offering unique steric and electronic properties for advanced chemical research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry, agrochemical development, and the creation of novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates with constrained ring structures.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclobutane core can contribute to specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Flavor and Fragrance Chemistry: Potential intermediate for synthesizing complex aroma chemicals with unique sulfur-containing notes.
• Material Science Research: Investigated as a monomer or building block for polymers with tailored thermal and mechanical properties.
• Academic and R&D Laboratories: Employed in methodological studies and the synthesis of complex natural product analogs.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-(Methylthio)-, Methyl Ester, cis- (9Ci)
CAS No.	89945-43-7
Molecular Formula	C8H14O2S
Molecular Weight	174.26 g/mol
Synonyms	cis-3-(Methylthio)cyclobutanecarboxylic acid methyl ester; Methyl cis-3-(methylthio)cyclobutanecarboxylate; cis-Methyl 3-(methylthio)cyclobutanecarboxylate; 3-(Methylsulfanyl)cyclobutanecarboxylic acid methyl ester, cis-; (1r,3s)-3-(Methylsulfanyl)cyclobutanecarboxylic acid methyl ester; (1s,3r)-3-(Methylsulfanyl)cyclobutanecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 3-(Methylthio)-, Methyl Ester, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.