Description

1-(2-Hydroxy-3-Iodophenyl)Ethanone is a specialized iodinated aromatic ketone, serving as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phenolic hydroxyl and an iodine substituent, makes it a versatile building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those requiring iodinated aromatic scaffolds for biological activity or as a handle for further functionalization.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where the iodine atom can be pivotal for efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds due to its electron-rich aromatic system.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags where the iodine can be used for radiolabeling (e.g., with I-125) or as a site for cross-coupling reactions.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	1-(2-Hydroxy-3-Iodophenyl)Ethanone
CAS No.	89942-31-4
Molecular Formula	C8H7IO2
Molecular Weight	262.05 g/mol
Synonyms	2'-Hydroxy-3'-iodoacetophenone; 3-Iodo-2-hydroxyacetophenone; 1-(3-Iodo-2-hydroxyphenyl)ethanone; 2-Acetyl-6-iodophenol; 3-Iodosalicylacetophenone; Ethanone, 1-(2-hydroxy-3-iodophenyl)-; o-Hydroxy-m-iodoacetophenone
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxy-3-Iodophenyl)Ethanone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.