Description

2-Methyl-2-(3-(Trifluoromethyl)Phenyl)Propanenitrile is a specialized organic nitrile building block featuring a trifluoromethylphenyl group. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical ingredients and agrochemicals, where the trifluoromethyl group is crucial for enhancing biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions and cyano-group transformations for constructing complex organic molecules.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new reaction methodologies and developing novel fluorinated compounds.

Basic Information

Product Name	2-Methyl-2-(3-(Trifluoromethyl)Phenyl)Propanenitrile
CAS No.	89765-40-2
Molecular Formula	C11H10F3N
Molecular Weight	213.20 g/mol
Synonyms	2-Methyl-2-[3-(trifluoromethyl)phenyl]propanenitrile; α,α-Dimethyl-3-(trifluoromethyl)benzeneacetonitrile; 3-(Trifluoromethyl)phenylisobutyronitrile; 2-Methyl-2-(3-trifluoromethylphenyl)propionitrile; 2-(3-(Trifluoromethyl)phenyl)-2-methylpropanenitrile; 89765-40-2; α,α-Dimethyl-m-(trifluoromethyl)phenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(3-(Trifluoromethyl)Phenyl)Propanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container must be kept tightly sealed due to the compound's sensitivity to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.