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5-Bromo-2-Methoxyphenylboronic Acid CAS NO 89694-45-1


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CAS No.:89694-45-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Bromo-2-Methoxyphenylboronic Acid is a versatile organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures through cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or substituted phenyl motifs.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the bromo-methoxy substitution pattern is valuable for bioactivity.
  • Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs or organic photovoltaics.
  • Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis or as a scaffold for catalyst design.
  • Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and drug-target interactions.
  • Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name 5-Bromo-2-Methoxyphenylboronic Acid
CAS No. 89694-45-1
Molecular Formula C7H8BBrO3
Molecular Weight 230.86 g/mol
Synonyms (5-Bromo-2-methoxyphenyl)boronic acid; 2-Methoxy-5-bromophenylboronic acid; 5-Bromo-o-anisylboronic acid; B-(5-Bromo-2-methoxyphenyl)boronic acid; 89694-45-1; 5-Br-2-MeO-PhB(OH)2
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Quality Control

Our 5-Bromo-2-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain optimal purity and reactivity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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