Description

[1As,(-)]-1Aα,10,11,11Aα-Tetrahydrobenzo[6,7]Phenanthro[1,2-B]Oxirene is a high-purity, complex polycyclic oxirane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and synthetic intermediate for the development of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions due to its defined stereochemistry.
• Natural Product Synthesis: Serves as a core structural unit in the total synthesis of complex natural products containing polycyclic frameworks.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme mechanisms and protein interactions.
• Advanced Material Research: Investigated as a monomer or precursor for specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	[1As,(-)]-1Aα,10,11,11Aα-Tetrahydrobenzo[6,7]Phenanthro[1,2-B]Oxirene
CAS No.	89618-18-8
Molecular Formula	C19H14O
Molecular Weight	258.31 g/mol
Synonyms	(-)-Benzo[6,7]phenanthro[1,2-b]oxirene, 1a,2,3,10b-tetrahydro-; 1aα,10,11,11aα-Tetrahydrobenzo[6,7]phenanthro[1,2-b]oxirene; Tetrahydrobenzo[6,7]phenanthro[1,2-b]oxirene; Benzo[6,7]phenanthro[1,2-b]oxirene, tetrahydro-; (1aS,11aR)-1a,2,3,11a-Tetrahydrobenzo[6,7]phenanthro[1,2-b]oxirene; Chiral polycyclic oxirane; Phenanthrooxirene derivative.
EINECS	Contact for details

Quality Control

Our [1As,(-)]-1Aα,10,11,11Aα-Tetrahydrobenzo[6,7]Phenanthro[1,2-B]Oxirene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and handled with appropriate personal protective equipment to ensure product integrity and safety.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.