Description

2-Hydroxyphenylboronic Acid is a versatile organoboron compound featuring both a boronic acid and a phenolic hydroxyl group on an aromatic ring. This bifunctional structure makes it a valuable building block in organic synthesis, particularly for the formation of carbon-boron and carbon-carbon bonds via cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing advanced intermediates, active ingredients, and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl structures, a common motif in pharmaceuticals and organic electronic materials.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, including potential enzyme inhibitors and receptor ligands.
• Agrochemical Synthesis: Serves as a precursor in creating novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Employed in the development of boronate ester-based polymers, sensors, and self-healing materials.
• Chemical Biology & Proteomics: Utilized in the design of probes and inhibitors that target proteins with serine or threonine residues.
• Ligand for Catalysis: Can be used to prepare ligands for transition metal catalysts used in various asymmetric syntheses.

Basic Information

Product Name	2-Hydroxyphenylboronic Acid
CAS No.	89466-08-0
Molecular Formula	C6H7BO3
Molecular Weight	137.93 g/mol
Synonyms	(2-Hydroxyphenyl)boronic Acid; 2-Boronophenol; o-Hydroxyphenylboronic Acid; Salicylboronic Acid; 2-Hydroxybenzeneboronic Acid; B-(2-Hydroxyphenyl)boronic Acid; 2-Dihydroxyborylphenol
EINECS	Contact for details

Quality Control

Our 2-Hydroxyphenylboronic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent decomposition. For long-term storage, consider using a desiccator or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	~185-195 °C (dec.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.