Description

[1S,4Ar,6R,10R,13As,(-)]-1,2,3,4,4A,5,6,9,10,11,12,13A-Dodecahydro-1,6-Dihydroxy-4,4,13A-Trimethyl-9-Methylene-10,7-Metheno-7H-Benzocycloundecene-8,13-Dione is a complex diterpenoid compound with a unique benzocycloundecene core structure. This compound serves as a critical intermediate or reference standard in advanced organic synthesis and pharmaceutical research, particularly for the development of novel therapeutic agents. It is essential for research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex natural product derivatives and novel drug candidates.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore biological activity and optimize lead compounds.
• Process Chemistry: Serves as a benchmark or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Valuable reagent for universities and research institutes studying diterpene chemistry, total synthesis, and biocatalysis.

Basic Information

Product Name	[1S,4Ar,6R,10R,13As,(-)]-1,2,3,4,4A,5,6,9,10,11,12,13A-Dodecahydro-1,6-Dihydroxy-4,4,13A-Trimethyl-9-Methylene-10,7-Metheno-7H-Benzocycloundecene-8,13-Dione
CAS No.	89354-63-2
Molecular Formula	C₂₀H₂₆O₄
Molecular Weight	330.42 g/mol
Synonyms	(-)-Kolavenol; Kolavenol; (1S,4aR,6R,10R,13aS)-1,2,3,4,4a,5,6,9,10,11,12,13a-Dodecahydro-1,6-dihydroxy-4,4,13a-trimethyl-9-methylene-10,7-metheno-7H-benzocycloundecene-8,13-dione; 7H-Benzocycloundecene-8,13-dione, 1,2,3,4,4a,5,6,9,10,11,12,13a-dodecahydro-1,6-dihydroxy-4,4,13a-trimethyl-9-methylene-10,7-metheno-, (1S,4aR,6R,10R,13aS)-; Labdane diterpenoid derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques to confirm identity and purity. Certificates of Analysis (COA) detailing specific test results are available upon request. We support development projects requiring material suitable for use under GMP or ISO 9001 guided frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.