Description

2'-Bromo-4-Fluoro-Biphenyl is a high-purity halogenated biphenyl derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers and liquid crystals for electronic displays.
• Organic Light-Emitting Diodes (OLEDs): Employed in the research and manufacture of electron-transport materials and host materials for OLED devices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create more complex biaryl structures.
• Chemical Research: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	2'-Bromo-4-Fluoro-Biphenyl
CAS No.	89346-54-3
Molecular Formula	C12H8BrF
Molecular Weight	251.10 g/mol
Synonyms	2-Bromo-4'-fluorobiphenyl; 4-Fluoro-2'-bromobiphenyl; (2-Bromophenyl)(4-fluorophenyl); 1-Bromo-2-(4-fluorophenyl)benzene; Biphenyl, 2'-bromo-4-fluoro-; 2-(4-Fluorophenyl)bromobenzene; 4-Fluorophenyl-2-bromophenyl
EINECS	Contact for details

Quality Control

Our 2'-Bromo-4-Fluoro-Biphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.