Description

2-(4-Nitro-3-[(Phenylsulfonyl)Methyl]Phenyl)-1,3-Dioxolane is a specialized organic intermediate featuring a dioxolane-protected aldehyde group and a phenylsulfonylmethyl moiety, making it a valuable synthon for complex molecular construction. Its structure is critical for applications requiring the controlled introduction of aromatic nitro and sulfone functionalities, which are pivotal in advanced synthesis. This compound is primarily sought by pharmaceutical R&D and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and high-value agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging its nitro-aromatic and sulfone groups.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology Probes: Utilized in creating molecular probes for studying enzyme inhibition or cellular pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise, multi-step organic transformations.

Basic Information

Product Name	2-(4-Nitro-3-[(Phenylsulfonyl)Methyl]Phenyl)-1,3-Dioxolane
CAS No.	89303-15-1
Molecular Formula	C₁₇H₁₇NO₆S
Molecular Weight	363.39 g/mol
Synonyms	1,3-Dioxolane, 2-[4-nitro-3-[(phenylsulfonyl)methyl]phenyl]-; 2-(4-Nitro-3-(phenylsulfonylmethyl)phenyl)-1,3-dioxolane; 4-Nitro-3-((phenylsulfonyl)methyl)benzaldehyde ethylene acetal; Benzaldehyde, 4-nitro-3-((phenylsulfonyl)methyl)-, ethylene acetal; NSC 406306
EINECS	Contact for details

Quality Control

Our 2-(4-Nitro-3-[(Phenylsulfonyl)Methyl]Phenyl)-1,3-Dioxolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.