Description

Ethanone, 2-Chloro-2,2-Difluoro-1-(4-Methylphenyl)- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoromethyl and chloro substituents, enabling precise molecular construction. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro moiety can enhance metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for synthesizing fluorinated polymers or liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce complex fluorinated motifs into target molecules.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethanone, 2-Chloro-2,2-Difluoro-1-(4-Methylphenyl)- (9Ci)
CAS No.	89264-09-5
Molecular Formula	C9H7ClF2O
Molecular Weight	204.60 g/mol
Synonyms	2-Chloro-2,2-difluoro-1-(4-methylphenyl)ethanone; 2-Chloro-2,2-difluoro-1-p-tolylethanone; 1-(4-Methylphenyl)-2-chloro-2,2-difluoroethanone; α-Chloro-α,α-difluoro-4-methylacetophenone; p-Methyl-α,α-difluoro-α-chloroacetophenone; 4-Methyl-α,α-difluoro-α-chloroacetophenone; 89264-09-5 (CAS)
EINECS	Contact for details

Quality Control

Every batch of Ethanone, 2-Chloro-2,2-Difluoro-1-(4-Methylphenyl)- (9Ci) is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.