Description

1-(1-Bromomethyl-Vinyl)-4-Chloro-Benzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a reactive bromomethyl-vinyl group and a chloro-substituted benzene ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small molecule drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive vinyl and aryl halide functionalities.
• Ligand and Catalyst Development: Utilized in the preparation of novel phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.
• Chemical Research & Development: A valuable reagent for exploring new organic transformations and constructing complex, polyfunctional molecules in academic and industrial labs.

Basic Information

Product Name	1-(1-Bromomethyl-Vinyl)-4-Chloro-Benzene
CAS No.	89220-51-9
Molecular Formula	C9H8BrCl
Molecular Weight	231.52 g/mol
Synonyms	4-Chloro-α-(bromomethyl)styrene; 1-(Bromomethyl)-1-(4-chlorophenyl)ethene; (1-Bromovinyl)methyl-4-chlorobenzene; p-Chloro-α-(bromomethyl)styrene; 4-Chlorobenzylidene(bromomethyl)methane; 89220-51-9; 1-(1-Bromomethylvinyl)-4-chlorobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-(1-Bromomethyl-Vinyl)-4-Chloro-Benzene is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and your specific research or production requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.