Description

Ethyl 2-Chloro-3-Hydroxypropionate is a versatile bifunctional ester intermediate, combining a reactive chloro group with a hydroxyl functionality. This unique structure makes it a valuable building block for the synthesis of more complex molecules in fine chemical and pharmaceutical manufacturing. It is particularly sought after by R&D chemists and production specialists in the agrochemical, pharmaceutical, and specialty polymer industries for constructing active ingredients and functional monomers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly β-blockers and other cardiovascular drugs.
• Agrochemical Synthesis: Serves as a building block for herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Used to introduce hydroxyl and ester groups into polymer chains, enhancing properties like adhesion, cross-linking potential, and biocompatibility.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and complex organic compounds requiring chiral centers.
• Cross-linking Agent: Functions in coatings, resins, and adhesives formulations where its dual functionality can promote curing and network formation.
• Chemical Research: A valuable reagent in organic synthesis laboratories for exploring new reaction pathways and creating novel molecular architectures.

Basic Information

Product Name	Ethyl 2-Chloro-3-Hydroxypropionate
CAS No.	89181-28-2
Molecular Formula	C5H9ClO3
Molecular Weight	152.58 g/mol
Synonyms	2-Chloro-3-hydroxypropionic acid ethyl ester; Ethyl 2-chloro-3-hydroxypropanoate; 3-Hydroxy-2-chloropropionic acid ethyl ester; Ethyl 3-hydroxy-2-chloropropionate; 2-Chloro-3-hydroxy-propionic acid ethyl ester; Glycidic acid ethyl ester, 2-chloro-; (RS)-Ethyl 2-chloro-3-hydroxypropionate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-3-Hydroxypropionate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure consistent purity, identity, and performance. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical properties. Our quality commitment supports compliance with cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.20 - 1.25
Refractive Index (20°C)	1.440 - 1.450

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.