Description

7-O,21-o-Diacetyl-21-o-De(3-Carboxy-1-Oxo-2-Propenyl)-2-Demethyl-2-Methoxy-24-Methylhygrolidin is a high-purity, structurally complex chemical intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the research and development of novel pharmacologically active molecules, particularly within the macrolide and polyketide structural classes. It is primarily needed by pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers focused on developing new therapeutic agents, including antibiotics and anti-cancer compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel macrolide antibiotics and other complex bioactive molecules.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Bioconjugation & Prodrug Development: The reactive functional groups enable its use in creating targeted drug delivery systems or prodrug formulations.
• Academic & Institutional Research: Employed in universities and research institutes for studying complex organic reaction mechanisms and natural product synthesis.
• Process Chemistry Development: Used by fine chemical manufacturers to develop and scale up efficient synthetic routes for complex active pharmaceutical ingredients (APIs).
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	7-O,21-o-Diacetyl-21-o-De(3-Carboxy-1-Oxo-2-Propenyl)-2-Demethyl-2-Methoxy-24-Methylhygrolidin
CAS No.	88899-57-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	21-De(3-Carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methylhygrolidin 7,21-diacetate; 7,21-Di-O-acetyl-21-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methylhygrolidin; A derivative of Hygrolidin; Methylhygrolidin derivative; Complex macrolide intermediate; Antibiotic synthesis intermediate
EINECS	Contact for details

Quality Control

Our 7-O,21-o-Diacetyl-21-o-De(3-Carboxy-1-Oxo-2-Propenyl)-2-Demethyl-2-Methoxy-24-Methylhygrolidin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.