Description

(2S,3R,4R,4Aα,8Aβ)-4-Acetyl-3,4,4A,5,6,7,8,8A-Octahydro-2β,7β-Dihydroxy-2α,4,5α,7α-Tetramethyl-3-[(R)-1-Methylpropyl]-1(2H)-Naphthalenone is a complex, stereochemically defined sesquiterpenoid derivative with a unique decalin core structure. This compound is of significant interest as a high-value chemical intermediate and a potential precursor for the synthesis of novel bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of complex natural products and novel drug candidates, particularly in anti-inflammatory or anti-infective research.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies due to its intricate stereochemistry and functional groups.
• Process Chemistry Development: Employed in the development and optimization of synthetic routes for complex organic molecules, including scale-up studies.
• Fine Chemical Synthesis: Acts as a specialized intermediate in the multi-step synthesis of high-value, low-volume specialty chemicals and flavors/fragrances.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis methodology, total synthesis, and chemical biology.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2S,3R,4R,4Aα,8Aβ)-4-Acetyl-3,4,4A,5,6,7,8,8A-Octahydro-2β,7β-Dihydroxy-2α,4,5α,7α-Tetramethyl-3-[(R)-1-Methylpropyl]-1(2H)-Naphthalenone
CAS No.	88899-17-6
Molecular Formula	C21H34O4
Molecular Weight	350.50 g/mol
Synonyms	4-Acetyl-3,4,4a,5,6,7,8,8a-octahydro-2,7-dihydroxy-2,4,5,7-tetramethyl-3-(1-methylpropyl)-1(2H)-naphthalenone; (2S,3R,4R,4aα,8aβ)-4-Acetyl-3,4,4a,5,6,7,8,8a-octahydro-2β,7β-dihydroxy-2α,4,5α,7α-tetramethyl-3-[(R)-1-methylpropyl]-1(2H)-naphthalenone; 1(2H)-Naphthalenone, 4-acetyl-3,4,4a,5,6,7,8,8a-octahydro-2,7-dihydroxy-2,4,5,7-tetramethyl-3-(1-methylpropyl)-, (2S,3R,4R,4aα,8aβ)-; A sesquiterpenoid naphthalenone derivative.
EINECS	Contact for details

Quality Control

Every batch of (2S,3R,4R,4Aα,8Aβ)-4-Acetyl-3,4,4A,5,6,7,8,8A-Octahydro-2β,7β-Dihydroxy-2α,4,5α,7α-Tetramethyl-3-[(R)-1-Methylpropyl]-1(2H)-Naphthalenone is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with client specifications and high research standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect against moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.