Description

2-Bromo-2-Phenyl-1-(γ-Fluorophenyl)-Ethanone is a specialized fluorinated bromoketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex pharmaceutical intermediates and agrochemicals, enabling the introduction of both bromine and fluorine functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aryl ketone motifs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the fluorophenyl group enhances biological activity and metabolic stability.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions due to the reactive bromine atom.
• Ligand & Catalyst Development: Utilized as a starting material for synthesizing novel chiral ligands or organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the properties and reactivities of fluorinated organic molecules.

Basic Information

Product Name	2-Bromo-2-Phenyl-1-(γ-Fluorophenyl)-Ethanone
CAS No.	88675-31-4
Molecular Formula	C14H10BrFO
Molecular Weight	293.13 g/mol
Synonyms	2-Bromo-2-phenyl-1-(4-fluorophenyl)ethanone; α-Bromo-4-fluorodesoxybenzoin; 4-Fluoro-α-bromodesoxybenzoin; 1-(4-Fluorophenyl)-2-bromo-2-phenylethanone; 2-Bromo-1-(4-fluorophenyl)-2-phenylethanone; (4-Fluorophenyl)(bromophenyl)methanone; γ-Fluorophenyl Bromophenyl Ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-Phenyl-1-(γ-Fluorophenyl)-Ethanone is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.